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Weichteilsarkome des Erwachsenen 9783805573948

Weichteilsarkome des Erwachsenen

Standards, Molekularbiologie, Perspektiven

ISBN-10: 3805573944
ISBN-13: 9783805573948
Also available at
Note: Not guaranteed to come with supplemental materials (access codes, CDs, DVDs)
Product Description: Obwohl Weichteilsarkome zu den seltenen bösartigen Tumoren gehören, sind sie aufgrund ihrer Lokalisationsvielfalt, des heterogenen tumorbiologischen Verhaltens und der ausgeprägten Resistenz gegenüber einer Bestrahlungs- und Chemotherapie sowohl diagnostisch als auch therapeutisch sehr oft problematisch. Hieraus ergibt sich die Notwendigkeit, nach neuen klinisch relevanten Prognosemarkern, Therapieindikatoren und Behandlungsstrategien zu suchen. Dieses Buch verfolgt das Ziel, neben den gegenwärtig etablierten Diagnose-, Prognose- und Behandlungsstandards neue tumorbiologische Erkenntnisse zu vermitteln und diese in ihrer Wertigkeit für die Diagnostik und Therapie von Patienten mit Weichteilsarkomen einzuschätzen. Der Bogen wird dabei von Angiogenese- und Apoptosefaktoren über molekular- und zytogenetische Besonderheiten bis hin zu Reparatur- und Zellzyklusmarkern gespannt. Darauf basierend werden gentherapeutische Behandlungsstrategien unter Berücksichtigung aktueller klinischer Studien dargestellt. Dieser Band ist sowohl für Kliniker, die in der Diagnostik und Behandlung von Weichteilsarkomen tätig sind, als auch für medizinisch interessierte Naturwissenschaftler sowie für Studenten der naturwissenschaftlichen und medizinischen Studienfächer konzipiert. Die Monografie soll diesen Gruppen ein Leitfaden für die Verbindung zwischen Klinik und Grundlagenforschung sein und damit den Nutzen einer Zusammenarbeit von Medizinern und Molekularbiologen sichtbar machen.

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PAGES: 206

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